Home Research Publications People Resources Courses Biological Sciences

Judith A. Cole, Ph.D. Associate Professor Department of Biological Sciences 3700 Walker Ave 239 Ellington Hall The University of Memphis Memphis, TN jcole2@memphis.edu 901.678.1363 This site is updated monthly. The University of Memphis, a Tennessee Board of Regents institution, is an Equal Opportunity/Affirmative Action University. It is committed to education of a non-racially identifiable student body.

Research Interests · G protein-coupled receptors and receptor tyrosine kinases · PTH and EGF regulation of epithelial function · Biased agonism and the regulation of bone cell function Research Summary The research focus in my lab is on the cross-talk between G protein-coupled receptors and receptor tyrosine kinases and their use of the mitogen-activated protein kinase ERK to regulate cellular functions. An important aspect of signal transduction research involves identifying the regulatory molecules connecting a receptor with a change in the rate of a physiological function. While there are literally thousands of receptor molecules, there are substantially fewer regulatory molecules. Thus cells must find a way to interpret differences in the size, duration and subcellular location of a signal in order to produce an appropriate response. Recent Publications from the Cole lab Poole, NM, Nyindodo-Ogari L, Kramer C, Coons LB and Cole JA Effects of tick saliva on the migratory and invasive activity of Saos-2. Ticks Tick Borne-Dis 4:120-127, 2013.  McCanless JD, Jennings LK, Bumgardner JD, Cole JA, Haggard WO. Hematoma-inspired alginate-platelet releasate-CaPO(4) composite: initiation of the inflammatory-mediated response associated with fracture repair in vitro and ex vivo injection delivery. J Mater Sci Mater Med. 23(8):1971-81, 2012. Information Links · Visit the Department of Biological Sciences Website to learn more about the Graduate Program · The Bioinformatics Program providing tools to understand complex biological systems · The W. Harry Feinstone Center for Genomic Research a focal point for functional genomics at the University of Memphis and in the Memphis scientific community · The Integrated Microscopy Center provides microscopy expertise to the University and the Memphis scientific community · The University of Memphis the flagship school of the Tennessee Board of Reagents · The City of Memphis the Bluff City, home of St Jude Children’s Research Hospital, The National Civil Rights Museum, Elvis, and the Blues .