My current research projects include laboratory biomechanical testing, kinematic and kinetic analysis of human motion and computational biomechanical modeling.
Williams JL, Gomaa ST: Using multibody dynamics to design total knee replacement implants. Computational Biomechanics for Medicine – Models, Algorithms and Implementation. Eds. Wittek A, Miller K, Nielsen PMF. Springer. ISBN 978-1-4614-6350-4, Expected publication date: May, 2013.
Mihalko WM, Conner DJ, Benner R, Williams JL: How Does TKA Kinematics Vary With Transverse Plane Alignment Changes in a Contemporary Implant? Clin Orthop Relat Res 470:186–192, 2012.
Sanford BA, Zucker-Levin AR, Williams JL, Mihalko WM, Jacobs EL: Principal component analysis of knee kinematics and kinetics after anterior cruciate ligament reconstruction. Gait & Posture. 2012 Jul;36(3):609-13. Epub 2012 Jul 6.
Mihalko WM, Williams JL: Total knee arthroplasty kinematics may be assessed using computer modeling: a feasibility study. Orthopedics; 35(10):40-4, 10/2012 (PDF).
Mihalko WM, Creek AT, Mary MN, Williams JL, Komatsu DE: Mechanoreceptors Found in a Posterior Cruciate Ligament from a Well Functioning Total Knee Arthroplasty Retrieval. J Arthoplasty 26(3): 504.e9-504.e12, April 2011.
Mihalko WM, Williams JL: Computer Modeling to Predict Effects of Implant Malpositioning During TKA. Orthopedics 33 (10/Supplement): 71-75, 2010 (PDF).
Williams JL, Knox DA, Teeter MG, Holdsworth DW, Mihalko WM: Evidence that In Vivo Wear Damage Alters Kinematics and Contact Stresses in a Total Knee replacement. Journal of Long-Term Effects of Medical Implants 20(1):45-50, 2010.
Lindsey JA, Conner D, Godleski P, Perkinson B, Mihalko WM, Williams JL: Patellar Button Wear Patterns in Well-Functioning Total Knee Arthroplasty Retrievals. Journal of Long-Term Effects of Medical Implants 20(1): 75-81, 2010.
Recent Student Theses
Sanford, Brooke A: An Assessment of Tibiofemoral Kinematics and Kinetics Following Anterior Cruciate Ligament Reconstruction, Ph.D. Dissertation, 2013
Conner, Devin J: Using Computer Assisted Tomography to Acquire More Detailed Subject Specific Information for Kinematic Analysis, M.S. Thesis, 2012 (PDF)
Knox, David Alderson: Correlation Between Computed Contact Parameters and Wear Patterns on a Retrieved UHMWPE Tibial Insert, M.S. Thesis, 2011 (PDF)
Connor, John M: Experimental Kinematic Analysis of Cadaver Knees Using a Knee Simulator and Surgical Navigation System, M.S. Thesis, 2011 (PDF)
Future Students: How to apply to the University of Memphis
I was born in South Africa, raised in The Netherlands and completed the last years of secondary education in Japan. In 1975 I received my Bachelor's degree in Biology from the University of Hawaii at Manoa in Honolulu. After working as a research associate in the Department of Surgery of the University of Hawaii at Saint Francis Hospital, I married Lillian Kubota in June, 1976. My wife and I decided to accept an offer of a National Institutes of Health Fellowship to attend the Department of Biomedical Engineering at Northwestern University in Evanston, Illinois, where I obtained a Master's and subsequently a Ph.D degree in Theoretical and Applied Mechanics.
During my five years at Northwestern University, I performed an experimental and theoretical study of the anisotropic and auxetic mechanical properties of trabecular bone under the guidance of Dr. Jack Lewis. The results of this work were published in the ASME Journal of Biomechanical Engineering. My Doctoral studies focused on developing a nonlinear dynamic finite element model of the human cervical spine for impact acceleration analysis under the direction of Dr. Ted Belytschko for a project sponsored by the Aerospace Medical Research Laboratory, Wright-Patterson Air Force Base in Ohio. This work was aimed at developing a model of the spine for testing restraint system designs and designs of helmet-mounted heads-up displays for jet pilots subjected to canopy bird strikes, aircraft ditching at sea or seat ejection. The results of this work were published as reports by the Aerospace Medical Research Laboratory, subsequently renamed the Harry G. Armstrong Aerospace Medical Research Laboratory and in the ASME Journal of Biomechanical Engineering.
After completing my Ph.D. in 1981, I accepted a position as an Assistant Professor of Mechanical Engineering at Northeastern University in Boston, where I taught mechanics related courses. In 1985 I accepted a position as Assistant Professor of Mechanical and Aerospace Engineering at the Syracuse University in Syracuse, New York, where I taught vibration theory, senior design, and performed experimental and theoretical research on the nondestructive evaluation of bone and bone-PMMA composites using ultrasound. After several years of teaching mechanical engineering I accepted a position in 1988 as Assistant Professor of Orthopaedic Surgery Research and Director of the McKay Laboratory of Orthopaedic Surgery. In 1995 I moved to Kansas City, Missouri to direct the Dixon-Diveley Laboratory of Orthopaedic Surgery Research at Truman Medical Center and to serve as Associate Professor of Orthopaedic Surgery and Adjunct Associate Professor of Oral Biology at the University of Missouri.
In 2005 I joined DePuy Orthopaedics, A Johnson and Johnson Company, at their plant in Warsaw, Indiana, as a research staff engineer. At DePuy I gained experience in the design, development and manufacturing practices of a large international orthopaedic medical device industry. During this time I also began working closely with LifeModeler, a software company in California, on projects aimed at enhancing their multibody dynamics models for analyzing the performance of orthopaedic implants in the human skeletal system.
Since 2008 I serve as Professor of Biomedical Engineering at the University of Memphis in Memphis, Tennessee, where I teach biomechanics and design related courses. My graduate students and I collaborate on research projects with UM faculty in Biomedical and Electrical Engineering and with UTHS faculty in orthopaedic surgery and physical therapy.
Knee Joint Prosthesis. EP2324798B1. Pub. Date: Aug 22, 2012.
Orthopaedic knee prosthesis having controlled condylar curvature. US 8236061B2. Pub. Date: Aug 07, 2012.
Knee prostheses with enhanced kinematics. US 8202323B2. Pub. Date June 19, 2012.
Posterior cructiate-retaining orthopaedic knee prosthesis having controlled condylar curvature. US Utility Patent No. 8192498. Pub. Date June 05, 2012.
Posterior Stabilized Orthopaedic Knee Prosthesis Having Controlled Condylar Curvature. US8187335B2. Pub. Date May 29, 2012.
Knee Joint Prosthesis. EP2140839B1. Pub. Date: Nov 16, 2011.
Antero-Posterior Placement of Axis of Rotation for a Rotating Platform. US Utility Patent No.: US7981159B2. Pub. Date: July 19, 2011.
Knee Replacement System. European Patent No.: EP 2145605B1. Pub. Date Sept 9, 2011.
Page last updated 17 February 2013